Recent Entries
-
Pronalyse Unveils Protein Drug Modification Analysis to Move Yo
by Kim YoungPronalyse is a new division of Creative Proteomics, which is an integrated CRO company with rich experience in providing drug development service for over 10 years. The company has recently announced Protein Drug Modification Analysis service to help researchers determine the modification type,... -
Research Progress of Targeted Protein Degradation Technology
by Kim YoungThe mode of action of currently developed drugs is mostly to achieve the purpose of disease treatment by inhibiting or enhancing the activity of target proteins. However, these drugs have to bind to the active site of target proteins to work. Among the known drug target proteins, only about 20% of t... -
Science: Blocking fibrin holds promise for the treatment of per
by Kim YoungIn a new study, researchers from the National Institute of Dental Craniofacial Research (NIDCR) have found that blocking the function of a coagulation protein prevents bone loss caused by periodontal (gingival) disease in mice. According to animal and human data, they found that the accumulation of ... -
Epigenetics Data Analysis Service Now Available by CD Genomics’
by Kim YoungBioinformatics-analysis Platform belongs to CD Genomics, which provides reliable next-generation and third-generation high-throughput sequencing data analysis, comprehensive technology services, database construction, and other related data analysis business. The platform is a leading open solution ... -
BOC Sciences Proudly Declares High PseudoUridine Productivity
by Kim YoungBOC Sciences, well known as the largest supplier of pseudoUridine in the world, announces that its yearly output currently surpasses 500 kg, indicating reliable efficiency and high productivity. Along with the explosion of the COVID-19 pandemic, many vaccine companies have collabo... -
Protein-Based Fluorescent Nanoparticles Available Now
by Kim YoungFluorescent nanoparticles are those widely used for purposes of fluorescent imaging, mainly of cells and tissues. A strong fluorophore or fluorescent nanoparticles are internalized into cells so that they can be imaged. The only purpose of such fluorophores and nanomaterials is to render cells or ti... -
Firstly Uncovered Genetic Clues to Schizophrenia
by Kim YoungCornel University researchers recently made a breakthrough in the study on schizophrenia with human-derived cerebral organoids. Schizophrenia is a chronic brain disorder of hitherto unknown etiology, with typical symptoms usually appearing in early adulthood and affecting approximately 1% o... -
In Silico Techniques Are Boosting Drug Discovery
by Kim YoungThe phrase "in silico" is pseudo-Latin referring to silicon in computer chips and it has become a frequently used term describing biological or other experiments performed by computers. This is an evolution of traditional in vivo and in vitro models that were used to develop new ... -
Viagra may help to prevent Alzheimer's disease
by Kim YoungThe most common neurodegenerative disease is Alzheimer's disease (AD), often known as dementia. The loss of memory, learning ability, emotional regulation, and athletic ability is common in patients, all of which have a negative impact on health, families, and society. Currently, about 50 m... -
A "bad" bacteria in colon cancer may serve a "positive" role in
by Kim YoungImmunotherapy has been successfully applied clinically to treat a wide range of hematological and solid metastatic malignancies. The most widely used drugs targeting immune checkpoints, such as programmed cell death protein 1 (PD-1) and its ligand PD-L1, are effective in a subset of cancer pati... -
Matched Antibody Pairs and Their Applications
by Kim YoungAn antigen molecule could have multiple antigenic determinants, or known as epitopes. An antibody produced by the immune system can only bind to a specific epitope, while an antigen molecule could bind to different antibodies targeting different epitopes on the antigen. This unique feature has been ... -
How to achieve target delivery of mRNA drugs to organs, cells,
by Kim YoungCell Targeted Delivery In addition to organ-specific delivery, the researchers sought to target specific cell subpopulations in the liver by engineering ionizable lipid nanoparticles for selective delivery to hepatocytes and hepatic sinusoidal endothelial cells (LSECs). Increasing PEG content enhan...